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pentobarbital will reduce the extent or influence of brexpiprazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Double brexpiprazole dose above one-two months if administered with a robust CYP3A4 inducer.pentobarbital and daridorexant both maximize sedation. Modify Therapy/Keep track of Intently. Coadm